Reinforces Mastery- Features like Understanding Words, Chapter Objectives, Review Questions and Critical Thinking Questions assist students in their overall understanding of the material presented.

InnerConnections- These multipurpose illustrations, found at the ends of systems chapters, conceptually link the highlighted body system to every other system, reinforcing the dynamic interactions of groups of organs. These graphic representations review chapter concepts, make connections, and stress the "big picture" in learning and applying the concepts and facts of anatomy and physiology.

Reconnect- these symbols enable students to easily refer to material presented in earlier chapters that they will need to make sure they have mastered in order to understand the next concept to be introduced.

Visual learners will appreciate the number of illustrations in the Hole text (about 800 total figures versus about 600 in Marieb, Martini and Tortora). Hole's art is focused on the main concepts by using concise labeling methodology that keeps students from getting bogged down with excessive detail. Difficult concepts are broken down into easy-to-understand illustrations.

Clinical Applications- address common illnesses, such as migraines, neurological disorders, prostate enlargement, and breast cancer. Often Clinical Applications introduce molecular information, such as "Disease at the Organelle Level" and "Molecular Causes of Cardiovascular Disease."

Clinical Terms- Lists of related terms often used in clinical situations are at the end of most chapters. These terms, along with their phonetic pronunciations and brief definitions, expand understanding of medical terminology.

Life-Span Changes- included in every system chapter offer new and exciting discoveries about what happens to the human body as it ages, and new treatments in development.

Core concepts are emphasized and excessive detail is minimized. The narrative is written in a succint, get-to-the-point style. Technical vocabulary is minimized (Hole introduces about 1/2 the number of boldface key terms as Marieb, Martini and Tortora- 1700 new terms versus about 3,500).

Hole also introduces more basic biology for students with limited background in this area (see Chapter 3- Cells and Chapter 4- Cell Metabolism).